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Symbol Name ID |
Top2b
topoisomerase (DNA) II beta MGI:98791 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal neuronal migration |
abnormal telencephalon development |
disorganized cortical plate |
absent subplate |
decreased brain size |
abnormal hippocampus morphology |
abnormal hippocampus granule cell layer |
abnormal hippocampus pyramidal cell layer |
abnormal cerebral cortex morphology |
abnormal stratification in cerebral cortex |
small olfactory bulb |
abnormal innervation pattern to muscle |
abnormal motor neuron innervation pattern |
abnormal embryonic/fetal subventricular zone morphology |
abnormal photoreceptor outer segment morphology |
abnormal retina cone cell outer segment morphology |
abnormal retina rod cell outer segment morphology |
photoreceptor outer segment degeneration |
abnormal retina cone cell morphology |
retina cone cell degeneration |
abnormal retina rod cell morphology |
retina photoreceptor degeneration |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Top2btm1Jcw/Top2btm1Jcw | |||||||||||||||||||||||
| Top2btm2.1Jcw/Top2btm2.1Jcw | |||||||||||||||||||||||
| Tg(Dkk3-cre)D9Tfur/0 Top2btm2Jcw/Top2btm2Jcw (conditional) |
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| Top2btm2Jcw/Top2btm2.1Jcw Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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